Non-Invasive PDRN Delivery Protocol with Spicules | Arkana BTSAmpoule

In this video, I demonstrate a combined skin regeneration protocol using plant- based PDRN and the Arkana BTS biomicroneedling system – a modern, non-invasive transdermal delivery technology for active ingredients.

🔬 What makes this PDRN unique

Unlike traditional PDRN derived from salmon DNA, this protocol uses next-generation plant-based PDRN, developed using “green biotech” technology:

Centella Asiatica
Ginseng callus (biotechnological source)
Pine needles (Pinus densiflora)

This ensures:

✔️high biocompatibility
✔️minimal risk of sensitization
✔️strong anti-inflammatory and antioxidant effects
✔️a modern and ethical formulation

PDRN acts as a biological signaling molecule, activating skin regeneration processes:

stimulates A2A receptors
enhances collagen synthesis
improves microcirculation
supports DNA repair after oxidative and UV stress

⚙️ BTS Biomicroneedling System (Spicules)

derived from Spongilla lacustris sponge
coated with plant collagen (Golden Hibiscus)
remain active in the skin for up to 72 hours
create microchannels for active ingredient delivery
stimulate epidermal regeneration and fibroblast activity

✔️non-invasive alternative to microneedling
✔️accelerates cell renewal up to 5x
✔️improves skin structure, microcirculation, and oxygenation

🧪 Key Active Components (BTS Ampoule)

Adenosine – anti-age component that reduces muscle tone and promotes a natural lifting effect
Niacinamide – restores the skin barrier and provides anti-inflammatory action
Bifida Ferment Filtrate – supports the microbiome and skin regeneration
Peptides (Copper Tripeptide-1, Acetyl Hexapeptide-8) – stimulate collagen, “botox-like” effect
Sodium Hyaluronate – hydration and active ingredient transport
Botanical extracts (Ginseng, Hibiscus, Polygonum, Portulaca) – antioxidant and regenerative support

💎 Why this protocol is unique

✔️non-invasive delivery of active ingredients
✔️biostimulation + transport in one protocol
✔️prolonged effect (up to 72 hours)
✔️suitable for patients avoiding injections

👩🏼‍⚕️ Indications

dull, tired skin
signs of aging and loss of firmness
uneven texture and skin tone
during GLP-1 receptor agonist therapy
sensitive skin

✨ Results

✔️increased skin density and elasticity
✔️smoother texture and reduced pores
✔️improved facial contour
✔️healthy glow and vitality
✔️visible rejuvenation without downtime

🫒 Internal Support: Exo Nutri Power

To enhance and prolong the results of aesthetic procedures, I recommend combining external treatments with internal cellular support.

Exo Nutri Power is a next-generation nutraceutical that works through the gut–skin axis.

🔬 Composition:

exosomes from orange, kiwi, lemon, and papaya
inulin – a prebiotic supporting the microbiome
zinc – for cellular protection and regeneration

✔️contains 10 billion exosomes per capsule

💊 Benefits:

supports skin regeneration from within
balances the gut microbiome
reduces oxidative stress
accelerates post-procedure recovery
improves skin quality and resilience

Dr. Irina Kalnina-Dobrovolska:
“I work within the concept of integrative regenerative aesthetic medicine — combining topical, transdermal, and internal therapies to restore skin function on a cellular level.”

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